Apple, Samsung allowed to add products in U.S. patent lawsuit
















(Reuters) – A U.S. judge allowed Samsung Electronics Co Ltd to pursue claims the iPhone5 infringes its patents on Thursday, while also allowing Apple Inc to add claims that the Samsung Galaxy Note, Galaxy S III and the Jelly Bean operating system violate its patents.


The ruling by U.S. Magistrate Judge Paul Grewal in San Jose, California, was the latest development in a continuing legal war by Apple against manufacturers like Samsung whose products use Google Inc’s Android software.













Representatives for both Apple and Samsung declined comment.


The case is one of two patent infringement lawsuits pending in the U.S. District Court in San Jose by Apple against Samsung. An earlier lawsuit by Apple that related to different patents resulted in a $ 1.05 billion jury verdict against Samsung on August 24.


Apple filed the second lawsuit in February, alleging that various Samsung smartphone and tablet products including the Galaxy Nexus infringed eight of its patents.


Samsung denied infringement and filed a cross-complaint alleging that Apple’s iPhone and iPad infringed eight of its patents.


U.S. District Judge Lucy Koh issued a preliminary injunction against pretrial sales of the Nexus in June. But the U.S. Court of Appeals for the Federal Circuit overturned the sales ban on October 11.


Following the debut of the iPhone on September 21, Samsung sought to add it as an Apple product that infringed its patents. Apple moved likewise to add the Samsung Galaxy Note 10.1, Samsung Galaxy S III and the Jelly Bean operating system in connection with the Galaxy Nexus.


In his ruling Thursday, Grewal said Samsung acted with “reasonable diligence” in asking the court to allow it to add the iPhone 5 to the case.


Apple did not oppose adding the iPhone5. Nevertheless, Grewal warned Apple to “think twice before opposing similar amendments reflecting other newly released products — e.g. the iPad 4 and iPad mini — that Samsung may propose in the near future.”


The case is Apple Inc v. Samsung Electronics Co., Ltd., et al., U.S. District Court, Northern District of California, 12-cv-00630.


(Reporting By Nate Raymond in New York; Editing by Richard Pullin)


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Israel moves on reservists after rockets target cities
















GAZA/JERUSALEM (Reuters) – Israeli ministers were on Friday asked to endorse the call-up of up to 75,000 reservists after Palestinian militants nearly hit Jerusalem with a rocket for the first time in decades and fired at Tel Aviv for a second day.


The rocket attacks were a challenge to Israel‘s Gaza offensive and came just hours after Egypt‘s prime minister, denouncing what he described as Israeli aggression, visited the enclave and said Cairo was prepared to mediate.













Israel’s armed forces announced that a highway leading to the Gaza Strip and two roads bordering the enclave would be off-limits to civilian traffic until further notice.


Tanks and self-propelled guns were seen near the border area on Friday, and the military said it had already called 16,000 reservists to active duty.


Prime Minister Benjamin Netanyahu convened senior cabinet ministers in Tel Aviv after the rockets struck to decide on widening the Gaza campaign.


Political sources said ministers were asked to approve the mobilization of up to 75,000 reservists, in what could be preparation for a possible ground operation.


No decision was immediately announced and some commentators speculated in the Israeli media the move could be psychological warfare against Gaza’s Hamas rulers. A quota of 30,000 reservists had been set earlier.


Israel began bombing Gaza on Wednesday with an attack that killed the Hamas military chief. It says its campaign is in response to Hamas missiles fired on its territory. Hamas stepped up rocket attacks in response.


Israeli police said a rocket fired from Gaza landed in the Jerusalem area, outside the city, on Friday.


It was the first Palestinian rocket since 1970 to reach the vicinity of the holy city, which Israel claims as its capital, and was likely to spur an escalation in its three-day old air war against militants in Gaza.


Rockets nearly hit Tel Aviv on Thursday for the first time since Saddam Hussein’s Iraq fired them during the 1991 Gulf War. An air raid siren rang out on Friday when the commercial centre was targeted again. Motorists crouched next to cars, many with their hands protecting their heads, while pedestrians scurried for cover in building stairwells.


The Jerusalem and Tel Aviv strikes have so far caused no casualties or damage, but could be political poison for Netanyahu, a conservative favored to win re-election in January on the strength of his ability to guarantee security.


“The Israel Defence Forces will continue to hit Hamas hard and are prepared to broaden the action inside Gaza,” Netanyahu said before the rocket attacks on the two cities.


Asked about Israel massing forces for a possible Gaza invasion, Hamas spokesman Sami Abu Zuhri said: “The Israelis should be aware of the grave results of such a raid and they should bring their body bags.”


Officials in Gaza said 28 Palestinians had been killed in the enclave since Israel began the air offensive with the declared aim of stemming surges of rocket strikes that have disrupted life in southern Israeli towns.


The Palestinian dead include 12 militants and 16 civilians, among them eight children and a pregnant woman. Three Israelis were killed by a rocket on Thursday. A Hamas source said the Israeli air force launched an attack on the house of Hamas’s commander for southern Gaza which resulted in the death of two civilians, one a child.


SOLIDARITY VISIT


A solidarity visit to Gaza by Egyptian Prime Minister Hisham Kandil, whose Islamist government is allied with Hamas but also party to a 1979 peace treaty with Israel, had appeared to open a tiny window to emergency peace diplomacy.


Kandil said: “Egypt will spare no effort … to stop the aggression and to achieve a truce.”


But a three-hour truce that Israel declared for the duration of Kandil’s visit never took hold. Israel said 66 rockets launched from the Gaza Strip hit its territory on Friday and a further 99 were intercepted by the Iron Dome anti-missile system.


Israel denied Palestinian assertions that its aircraft struck while Kandil was in the enclave.


Israel Radio’s military affairs correspondent said the army’s Homefront Command had told municipal officials to make civil defence preparations for the possibility that fighting could drag on for seven weeks. An Israeli military spokeswoman declined to comment on the report.


The Gaza conflagration has stoked the flames of a Middle East already ablaze with two years of Arab revolution and a civil war in Syria that threatens to leap across borders.


It is the biggest test yet for Egypt’s new President Mohamed Mursi, a veteran Islamist politician from the Muslim Brotherhood who was elected this year after last year’s protests ousted military autocrat Hosni Mubarak.


Egypt’s Muslim Brotherhood are spiritual mentors of Hamas, yet Mursi has also pledged to respect Cairo’s 1979 peace treaty with Israel, seen in the West as the cornerstone of regional security. Egypt and Israel both receive billions of dollars in U.S. military aid to underwrite their treaty.


Mursi has vocally denounced the Israeli military action while promoting Egypt as a mediator, a mission that his prime minister’s visit was intended to further.


A Palestinian official close to Egypt’s mediators told Reuters Kandil’s visit “was the beginning of a process to explore the possibility of reaching a truce. It is early to speak of any details or of how things will evolve”.


Hamas fighters are no match for the Israeli military. The last Gaza war, involving a three-week long Israeli air blitz and ground invasion over the New Year period of 2008-2009, killed more than 1,400 Palestinians, mostly civilians. Thirteen Israelis died.


Tunisia’s foreign minister was due to visit Gaza on Saturday “to provide all political support for Gaza” the spokesman for the Tunisian president, Moncef Marzouki, said in a statement.


The United States asked countries that have contact with Hamas to urge the Islamist movement to stop its rocket attacks.


Hamas refuses to recognize Israel’s right to exist. By contrast, Palestinian President Mahmoud Abbas, who rules in the nearby West Bank, does recognize Israel, but peace talks between the two sides have been frozen since 2010.


Abbas’s supporters say they will push ahead with a plan to have Palestine declared an “observer state” rather than a mere “entity” at the United Nations later this month.


(Additional reporting by Maayan Lubell, Jeffrey Heller and Crispian Balmer in Jerusalem; Writing by Jeffrey Heller; Editing by Giles Elgood)


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Head vs. heart: Egypt's Gaza dilemma

The hostilities threatening to escalate into all-out war between Israel and Palestinian militants in Gaza concern the two antagonists first and foremost, but the course the fighting takes is likely to be equally consequential for Egyptian President Mohammed Morsi – and for his relations with the United States.


Egypt’s Islamist president finds himself pulled in competing directions by the head and the heart. The fighting this week – the result of heavy Israeli retaliation for escalating rocket fire from Gaza into southern Israel – has the Islamist Mr. Morsi in a tight spot: caught between his co-religionists across the border in Gaza, on one side, and Washington, upon which a struggling Egypt relies for economic and military assistance, on the other.


For some Middle East analysts, this could be a moment for Morsi to emerge and establish himself as a leader to be reckoned with in the unstable and leaderless post-Awakening Arab world. But successfully maneuvering this moment will take time. And with Israeli soldiers amassing on Gaza’s border, the analysts add, it’s unclear whether Morsi will have the chance to even take the leadership test the situation presents.


IN PICTURES: Gaza: battleground and daily life under Hamas' rule


“Morsi is definitely between the proverbial rock and hard place, but if he can pull together the elements to convince Hamas to stop the rockets … and he can defuse this situation, then I think he can emerge as a leader in the region,” says Aaron David Miller, a Middle East scholar at the Woodrow Wilson International Center in Washington. “But he needs time and space to try to do it, and I’m not sure the Israelis are going to allow him that time.”


The sudden flare-up involving Gaza and its Islamist leaders is also testing US influence in a region where the Arab Awakening has deposed a number of autocratic leaders more disposed to upholding a US-led system of security and stability – including former Egyptian President Hosni Mubarak – in favor of Islamist-led governments.


Morsi hails from the Muslim Brotherhood, as does Hamas, the militant Palestinian organization that governs Gaza. The rockets crashing into southern Israel have been lobbed by a collection of militant Islamist groups operating in Gaza, including some aligned with Iran. But after the Israelis launched retaliatory air strikes, including a strike that killed the Hamas military leader, Ahmed Jabari, Hamas has continued the barrage of rocket fire into Israel and the fighting has largely boiled down to a battle between Israel and Hamas.


Morsi has made his sympathies clear on Egyptian television, lamenting the spilling of Palestinian blood and railing against what he calls the Israeli “aggression.” But privately he is apparently sounding more amenable to trying to convince Hamas to stand down, perhaps by accepting a cease-fire. Morsi has spoken by phone with President Obama and Secretary of State Hillary Rodham Clinton several times this week, US officials say.


This is where Morsi’s head comes in. Egypt depends on the US for some $1.5 billion in annual assistance, not to mention Washington’s advocacy before international financial institutions – including the International Monetary Fund, where Egypt currently has a $4.5 billion loan under consideration.


Egypt’s relations with the US have not sailed through the stormy waters of the Egyptian revolution unscathed. The uncertainty and growing mistrust that now characterize what was once the solid core of US relations with the region were captured by Obama’s comment in an interview in September: “I don’t think we would consider [Egypt] an ally,” the president said, “but we don’t consider them an enemy,” either.


The turbulence has led some analysts to wonder if Morsi might be willing to jeopardize US assistance in order to pursue pro-Islamist – and more overtly anti-Israeli – policies. This week’s deadly violence between Israel and Hamas has led to some speculation that Morsi, who recalled Egypt’s ambassador to Israel, might be willing to take steps jeopardizing the Camp David peace accords between Egypt and Israel.


But experts like Mr. Miller point out that Egypt’s economic stability is linked to Camp David, since receipt of the substantial US aid, and favorable treatment with international financial institutions, are both products of the 1979 accords.


Without a treaty, there’s no special relationship with the US – whether or not it’s as an ally.


Morsi might take a number of steps to convince Hamas to pull back. He could agree to open the Egypt-Gaza border (this possibility is why Israel is pressing Egypt to block any passage of weapons, including replacement rocket launch pads, across its border) and he could work with Saudi Arabia and other patron states to up their financial assistance to Gaza, Miller says.


Morsi might then come out of the Gaza crisis with a much shinier image – the question now may be whether Israel is willing to hold back to see if Egypt’s Islamist leader is capable of this role.


IN PICTURES: Gaza: battleground and daily life under Hamas' rule



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The tailor behind Elvis Presley’s signature ’50s style dies in Memphis
















LOS ANGELES (TheWrap.com) – Bernard Lansky, the man who helped created Elvis Presley‘s signature fashion style in the ’50s – pegged pants and two-toned shoes – died Thursday in his Memphis home. He was at 85.


Presley frequented Lansky’s men’s fashion store on Beale Street – a popular spot for blues, rhythm and blues and jazz music – after years of admiring the clothing styles as a teenager working at a nearby theater.













“When I get rich, I’m going to buy you out,” Lanksy recalled Presley telling him before becoming a rock ‘n’ roll star. “Don’t buy me out,” the salesman responded. “Just buy from me.”


And that’s exactly what the musician did, just after Presley signed with Sun Records in 1954.


“I put his first suit on him and his last suit on him,” Lansky bragged.


“It’s a statement to say that he dressed one of the most influential entertainers of all time,” Julie Lansky, his granddaughter, told AP. “He knew that for any entertainer, they had to look different.”


Lansky’s success continued long after his most famous client died on August 16, 1977. After moving his shop to the Peabody Hotel in Memphis’ downtown district in 1981, he went on to dress musicians like B.B. King, Carl Perkins, Johnny Cash, ZZ Top, Kiss and Hootie and the Blowfish.


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Placebos Work Better On Stoics
















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Aches and pains getting you down? Or maybe they really tick you off. If that’s the case, maybe don’t look to a placebo to give you any relief. Because a new study shows that sugar pills are less effective for people who are quick to anger. The work appears in the journal Neuropsychopharmacology. [Marta PeciƱa et al, Personality Trait Predictors of Placebo Analgesia and Neurobiological Correlates]













For centuries, physicians have known that some patients improve when given fake medicine, like pills that contain no real drugs. But how can docs predict which of their cases are most likely to benefit from the ‘placebo effect’?


To find out, researchers ran 50 volunteers through a battery of personality tests. They then injected a bit of saltwater into the subjects’ muscles and told them they’d be getting a little something to relieve the resulting pain. Although that little something was actually a sham.


The researchers found that pretend meds don’t do much for people who tend toward hostility. They work best for folks who are naturally resilient, and altruistic.


The subjects who responded to the faux treatment actually produced more of the body’s own natural painkillers. That’s good news for the stoic, and one more thing for the angry to be mad about.


—Karen Hopkin


[The above text is a transcript of this podcast]
 


Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.


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News Summary: UK court overturns Facebook demotion
















PUNISHED: Britain‘s High Court ruled Friday that a man had been unfairly stripped of a management position and demoted for saying in a Facebook post that he was opposed to gay marriage.


COURT RULING: The court said the Trafford Housing Trust breached Adrian Smith‘s contract and a judge added that Smith had not done anything wrong. Smith had written on Facebook that gay weddings in churches would be “an equality too far.”













EVOLVING LAW: In Britain, same-sex couples can form civil partnerships that carry the same legal rights marriages do. The government plans to introduce legislation allowing civil marriages as well.


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France urges Mali to step up talks with rebels
















PARIS (AP) — France‘s president called Thursday for stepped-up talks between Mali’s government and any leaders from its breakaway north “who reject terrorism,” even as African nations geared up for a possible military operation against Islamic extremists there.


President Francois Hollande‘s comments suggested a growing openness to dialogue with the extremists, but he remained committed to supporting the military planning effort.













Northern Mali fell to Islamic extremists in April, after coup leaders toppled the government in Bamako, Mali‘s capital. Fearing that northern Mali could become the latest hotbed of terrorism, France has been a driving force in international efforts to bolster Mali’s army to drive the Islamists from power.


Hollande spoke with interim Mali President Dioncounda Traore by phone on Thursday, partly to detail European efforts to help strengthen Mali’s army.


In recent days, representatives from the most moderate of three al-Qaida-linked groups that control northern Mali have been meeting with Burkina Faso‘s president, appointed as a mediator.


“France reiterates its wish that political dialogue will intensify between Malian authorities and representatives of northern populations who reject terrorism,” Hollande’s office said in a statement. “The acceleration of this dialogue must accompany the progress in African military-planning efforts.”


Earlier this week, the African Union approved a plan that calls for 3,300 African troops to be deployed in order to win back Mali’s north. European countries including France and Germany have expressed a willingness to provide military trainers and logistics support, but have stopped short of committing combat troops.


France, like many European countries, fears that the arid, northern Sahel region of Mali could become a breeding ground for terrorism, where al-Qaida and its allies could plot hostage-takings and attacks in Europe or beyond.


France has millions of people whose families hail from former French colonies in north and west Africa. Authorities have long been concerned that French-born militants could travel abroad for terrorism training and return home later to possibly carry out attacks.


French authorities are already investigating two French citizens who were arrested in Mali and neighboring Niger and are suspected of seeking to join up with the al-Qaida-linked extremists, a judicial official told The Associated Press.


Ibrahim Ouattara, a 24-year-old native of the northern Paris suburb of Aubervilliers who has dual French and Malian nationality, was arrested inside Mali this month and remains in custody there, the official said.


Separately, a 27-year-old Frenchman was arrested in August in Niger and has since been handed over to authorities in France, the official said, speaking on condition of anonymity because she was not authorized to discuss terrorism cases publicly.


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Signs mount of possible Israeli invasion of Gaza

JERUSALEM (AP) — Israeli aircraft targeted rocket launching operations of Gaza militants early Friday as troops, tanks and armored personnel carriers massed near the Palestinian territory, signaling a ground invasion might be growing near.

Fighting between the two sides escalated sharply Thursday with a first-ever militant attack on the Tel Aviv area, menacing Israel's heartland. No casualties were reported there, but three people died in the country's rocket-scarred south when a projectile slammed into an apartment building.

The death toll in the densely populated Palestinian territory climbed to 19, including five children, according to Palestinian health officials, as waves of Israeli fighter planes and drones sent missiles hurtling down on suspected weapons stores and rocket-launching sites.

Early Friday, 85 missiles exploded within 45 minutes in Gaza City, sending black pillars of smoke towering above the coastal strip's largest city. The military said it was targeting underground rocket launching sites.

One missile hit the Interior Ministry, a symbol of Hamas power, and another hit an empty house belonging to a senior Hamas commander. Those strikes, together with an attack on a generator building near the home of Gaza's Hamas prime minister, Ismail Haniyeh, signaled that Israel was expanding its offensive beyond military targets.

The fighting has already widened the instability gripping a region in the throes of war and regime upheavals. It has straining already frayed relations with Egypt, which was sending its prime minister to Gaza later Friday in a show of solidarity with its militant Hamas rulers.

Israel and Hamas had largely observed an informal truce since Israel's devastating incursion into Gaza four years ago, but rocket fire and Israeli airstrikes on militant operations didn't halt entirely. The latest flare-up exploded into major violence Wednesday when Israel assassinated Hamas' military chief, following up with a punishing air assault meant to cripple the militants' ability to terrorize Israel with rockets.

The Israeli military reported early Friday that its aircraft had struck more than 350 targets since the beginning of its operation against Hamas' rocket operations.

After nightfall Thursday, several explosions shook Gaza City several minutes apart, a sign the strikes were not letting up. The military said the targets were about 70 underground rocket-launching sites.

The Israeli offensive has not deterred the militants from striking back with more than 400 rockets aimed at southern Israel. For the first time, they also unleashed the most powerful weapons in their arsenal — Iranian-made Fajr-5 rockets capable of reaching Tel Aviv.

The two rockets that struck closest to Tel Aviv appear to have landed in the Mediterranean Sea, defense officials said, and another hit an open area on Tel Aviv's southern outskirts.

No injuries were reported, but the rocket fire — the first in the area from Gaza — sowed panic in Tel Aviv and made the prospect of a ground incursion more likely. The government later approved the mobilization of up to 30,000 reservists for a possible invasion.

Israeli Prime Minister Benjamin Netanyahu said the army was hitting Hamas hard with what he called surgical strikes, and warned of a "significant widening" of the Gaza operation. Israel will "continue to take whatever action is necessary to defend our people," said Netanyahu, who is up for re-election in January.

At least 12 trucks were seen transporting tanks and armored personnel carriers toward Gaza late Thursday, and buses carrying soldiers headed toward the border area. Israeli TV stations said a Gaza operation was expected on Friday, though military officials said no decision had been made.

"We will continue the attacks and we will increase the attacks, and I believe we will obtain our objectives," said Lt. Gen. Benny Gantz, Israel's military chief.

An Israeli ground offensive could be costly to both sides. In the last Gaza war, Israel devastated large areas of the territory, setting back Hamas' fighting capabilities but also paying the price of increasing diplomatic isolation because of a civilian death toll numbering in the hundreds.

The current round of fighting is reminiscent of the first days of that three-week offensive against Hamas. Israel also caught Hamas off guard then with a barrage of missile strikes and threatened to follow up with a ground offensive.

Much has changed since then.

Israel has improved its missile defense systems, but it is facing a more heavily armed Hamas. Israel estimates the militants have 12,000 rockets, including more sophisticated weapons from Iran and from Libyan stockpiles plundered after the fall of Moammar Gadhafi's regime there last year.

Also, regional alignments have changed dramatically since the last Gaza war. Hamas has emerged from its political isolation as its parent movement, the region-wide Muslim Brotherhood, has risen to power in several countries in the wake of last year's Arab uprisings, particularly in Egypt.

Egypt recalled its ambassador to protest the Israeli offensive and ordered its prime minister to lead a senior delegation to Gaza on Friday in a show of support for Hamas.

At the same time, while relations with Israel have cooled since the toppling of longtime Egyptian leader Hosni Mubarak, Islamist President Mohammed Morsi has not brought a radical change in Egypt's policy toward Israel. He has promised to abide by Egypt's 1979 peace deal with Israel and his government has continued contacts with Israel through its non-Brotherhood members.

___

Laub reported from Gaza City, Gaza Strip.

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Why David Geffen is getting the “American Masters” treatment
















LOS ANGELES (TheWrap.com) – David Geffen is not a singer. Nor is he a movie star. Nor is he a writer.


Thus he would seem an odd subject for “American Masters,” a series devoted to artists ranging from Willa Cather to Woody Allen.













Yet series creator Susan Lacy claims that the mogul has had a profound impact on American popular culture that equals any of those figures. She pleads her case in “Inventing David Geffen,” which will be broadcast November 20 on PBS. The documentary had its premiere in Los Angeles on Tuesday night.


“He seems like a bit of an odd choice,” Lacy admitted to TheWrap. “But I have a degree in American Studies and I learned that the people with the most influence are often the ones behind the scenes.”


In Geffen, Lacy saw a figure like Alfred Stieglitz, a photographer whose lasting legacy was a series of modernist shows he held at his New York galleries that influenced visual arts in this country and brought cubism to the masses.


Some arm twisting must have been required to get the press-averse Geffen to emerge from semi-retirement to reflect on his career in movies, music and Broadway. Lacy said that part of the reason she was able to convince him to participate is that he was a fan of the series and had participated in her documentaries on figures such as Joni Mitchell.


“It wasn’t hard,” she said. “I knew from other people that he thinks my Leonard Bernstein documentary is one of the best documentaries anyone ever made. Mike Nichols told me that he makes everybody who stays with him watch it.”


In addition to Geffen, the documentary features interviews with his friends and colleagues — an A-list rolodex that includes Tom Hanks, Steven Spielberg, Elton John, Neil Young, Clive Davis, Barry Diller, and Irving Azoff. His sphere was huge, Lacy claims because his influence was tectonic.


By championing musicians such as Jackson Browne and Laura Nyro, Geffen put his own imprint on the emerging singer-songwriter movement in the 1970s. Later, Geffen managed to adapt to shifting tastes, by aligning himself with groups like Aerosmith and Guns ‘N Roses and helping to usher in the heavy metal craze. For more than 30 years, his labels – Asylum Records, Geffen Records, and DGC Records – represented the high-water mark for musicians, who clamored to get in the door.


“He had an incredible eye for talent,” Lacy said. “These people would have eventually found their way. But he helped them get there. He fixed their teeth and allowed them to write music that’s history.”


Though he made his name in music, Geffen also became a force in the theater and film businesses.


He enriched himself by producing hit musicals like “Cats” and “Dreamgirls,” and branched out into movies with memorable pictures like “Risky Business.” In 1994, he co-founded DreamWorks SKG, the studio behind Oscar-winners like “American Beauty” and “Saving Private Ryan.”


“In each decade, he has done something that has affected the culture,” Lacy said. “If I had to boil it down to one thing it would be his genius at business.”


It’s a mastery of deal-making and talent-scouting that has made him a very wealthy man, worth an estimated $ 5.5 billion. It is also a trajectory that Lacy maintains cannot be replicated in a more fractured media landscape, where mega-corporations wield disproportionate influence and are more interested in quarterly earnings than fostering rising stars.


“Even he would say that nobody could do what he did today,” Lacy said. “The times have changed so much. I asked him if he could raise $ 2 billion to start a new studio, and he said ‘absolutely not.’ And record companies, well, we know what happened to them. Behind all the conglomerates and corporations, to find someone with a genuine sensibility like David Geffen‘s would be impossible. He was unique.”


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Wormy Monkeys Had Healthier Intestines
















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In developed countries, we’ve mostly eliminated freeloaders like parasitic worms from our guts. But we also have the highest rates of inflammatory bowel disease, or IBD—when the immune system mistakenly attacks intestinal cells and friendly gut bacteria.













For years, docs suspected there might be a connection between IBD and our worm-free lifestyle. And a handful of studies have actually shown that infecting human patients with worms can reduce symptoms of the disease. But how?


To find out, researchers fed parasitic worm eggs to monkeys with chronic diarrhea and gut inflammation—similar to IBD. After infection, the monkeys’ immune systems kicked into high gear, pumping out more mucus than usual to fight the worms. But that response also helped heal the monkeys’ intestines—restoring healthy, diverse populations of gut bacteria and decreasing the diarrhea. Those results appear in the journal PLoS Pathogens. [Mara Jana Broadhurst et al, Therapeutic Helminth Infection of Macaques with Idiopathic Chronic Diarrhea Alters the Inflammatory Signature and Mucosal Microbiota of the Colon]


The researchers already have FDA approval to study the worms in human subjects. Interested patients can go to clinicaltrials.gov to sign up—and hopefully worm their way out of intestinal distress.


—Christopher Intagliata


[The above text is a transcript of this podcast]
 


Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.


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